袁骏华，青岛大学基础医学院特种医学系，博士，助理教授，特种医学学科秘书。

一、 个人简介

2020年6月于青岛大学取得特种医学专业医学博士学位，同年8月入职青岛大学基础医学院特种医学系。参与《运动医学》、《现代特种医学》、《高压氧医学》和《特种医学前沿进展》等本科及研究生授课工作。自2017年以来，以第一/共同第一作者发表论文7篇，参与发表论文十余篇，为《Medical Gas Research》杂志审稿专家。

二、 主要研究方向

高压氧与肥胖相关代谢疾病，脂肪因子对摄食和能量平衡的调控机制。

三、 代表性科研成果 (近五年SCI论文)

1. Yuan J#, Jiang Q#, Song L, Liu Y, Li M, Lin Q, Li Y, Su K, Ma Z, Wang Y, Liu D, Dong J*. L-Carnitine Is Involved in Hyperbaric Oxygen-Mediated Therapeutic Effects in High Fat Diet-Induced Lipid Metabolism Dysfunction. Molecules. 2020 Jan 1;25(1):176. doi: 10.3390/molecules25010176. PMID: 31906305; PMCID: PMC6982999.

2. Yuan JH#, Song LM, Liu Y, Li MW, Lin Q, Wang R, Zhang CS, Dong J*. The Effects of Hyperbaric Oxygen Therapy on Pelvic Radiation Induced Gastrointestinal Complications (Rectal Bleeding, Diarrhea, and Pain): A Meta-Analysis. Front Oncol. 2020 Apr 9;10:390. doi: 10.3389/fonc.2020.00390. PMID: 32328454; PMCID: PMC7160697.

3. Yuan JH#, Chen X#, Dong J*, Zhang D, Song K, Zhang Y, Wu GB, Hu XH, Jiang ZY, Chen P. Nesfatin-1 in the Lateral Parabrachial Nucleus Inhibits Food Intake, Modulates Excitability of Glucosensing Neurons, and Enhances UCP1 Expression in Brown Adipose Tissue. Front Physiol. 2017 Apr 24;8:235. doi: 10.3389/fphys.2017.00235. PMID: 28484396; PMCID: PMC5401881.

4. Zhang C#, Yuan J#, Lin Q, Li M, Wang L, Wang R, Chen X, Jiang Z, Zhu K, Chang X, Wang B*, Dong J*. Ghrelin in the lateral parabrachial nucleus influences the excitability of glucosensing neurons, increases food intake and body weight. Endocr Connect. 2020 Dec;9(12):1168-1177. doi: 10.1530/EC-20-0285. PMID: 33112816; PMCID: PMC7774750.

5. Song L#, Yuan J#, Liu Y, Zhang D, Zhang C, Lin Q, Li M, Su K, Li Y, Gao G, Ma R, Dong J*. Ghrelin system is involved in improvements in glucose metabolism mediated by hyperbaric oxygen treatment in a streptozotocininduced type 1 diabetes mouse model. Mol Med Rep. 2020 Nov;22(5):3767-3776. doi: 10.3892/mmr.2020.11481. Epub 2020 Sep 2. PMID: 32901885; PMCID: PMC7533472.

6. Wang R#, Yuan J#, Zhang C, Wang L, Liu Y, Song L, Zhong W, Chen X, Dong J*. Neuropeptide Y-Positive Neurons in the Dorsomedial Hypothalamus Are Involved in the Anorexic Effect of Angptl8. Front Mol Neurosci. 2018 Dec 18;11:451. doi: 10.3389/fnmol.2018.00451. PMID: 30618603; PMCID: PMC6305345.

7. Lv N#, Yuan J, Ji A, Shi L, Gao M, Cui L, Jiang Q*. Perfluorooctanoic acid-induced toxicities in chicken embryo primary cardiomyocytes: Roles of PPAR alpha and Wnt5a/Frizzled2. Toxicol Appl Pharmacol. 2019 Oct 15;381:114716. doi: 10.1016/j.taap.2019.114716. Epub 2019 Aug 21. PMID: 31445018.

8. Liu Y#, Zhang D#, Yuan J, Song L, Zhang C, Lin Q, Li M, Sheng Z, Ma Z, Lv F, Gao G, Dong J*. Hyperbaric Oxygen Ameliorates Insulin Sensitivity by Increasing GLUT4 Expression in Skeletal Muscle and Stimulating UCP1 in Brown Adipose Tissue in T2DM Mice. Front Endocrinol (Lausanne). 2020 Jan 31;11:32. doi: 10.3389/fendo.2020.00032. PMID: 32082261; PMCID: PMC7005601.

9. Li M#, Song L#, Yuan J, Zhang D, Zhang C, Liu Y, Lin Q, Wang H, Su K, Li Y, Ma Z, Liu D, Dong J*. Association Between Serum Insulin and C-Peptide Levels and Breast Cancer: An Updated Systematic Review and Meta-Analysis. Front Oncol. 2020 Oct 29;10:553332. doi: 10.3389/fonc.2020.553332. PMID: 33194614; PMCID: PMC7658676.

10. Zhang D#, Yu YJ, Xu FS, Yuan JH, Wang R, Zhang CS, Wang LX, Liu Y, Song LM, Liu JL, Dong J*. Recombinant betatrophin (Angptl8/lipasin) ameliorates streptozotocininduced hyperglycemia and βcell destruction in neonatal rats. Mol Med Rep. 2019 Nov;20(5):4523-4532. doi: 10.3892/mmr.2019.10719. Epub 2019 Oct 1. PMID: 31702044; PMCID: PMC6797976.

11. Su KZ#, Li YR, Zhang D, Yuan JH, Zhang CS, Liu Y, Song LM, Lin Q, Li MW, Dong J*. Relation of Circulating Resistin to Insulin Resistance in Type 2 Diabetes and Obesity: A Systematic Review and Meta-Analysis. Front Physiol. 2019 Nov 19;10:1399. doi: 10.3389/fphys.2019.01399. PMID: 31803062; PMCID: PMC6877503.

12. Jiang Q#, Xu X, Ni H, Guo Y, Yuan J, Zheng Y*. In Ovo Early-in-Life Inhalation Exposure to Gas/Aerosol with a Chicken Embryo Model. Methods Mol Biol. 2021;2326:197-201. doi: 10.1007/978-1-0716-1514-0_13. PMID: 34097269.

13. Xu HC#, Pang YC, Chen JW, Cao JY, Sheng Z, Yuan JH, Wang R, Zhang CS, Wang LX, Dong J*. Systematic Review and Meta-analysis of the Change in Ghrelin Levels After Roux-en-Y Gastric Bypass. Obes Surg. 2019 Apr;29(4):1343-1351. doi: 10.1007/s11695-018-03686-3. Erratum in: Obes Surg. 2019 Apr 10;: PMID: 30684171.

14. Sheng Z#, Cao JY, Pang YC, Xu HC, Chen JW, Yuan JH, Wang R, Zhang CS, Wang LX, Dong J*. Effects of Lifestyle Modification and Anti-diabetic Medicine on Prediabetes Progress: A Systematic Review and Meta-Analysis. Front Endocrinol (Lausanne). 2019 Jul 12;10:455. doi: 10.3389/fendo.2019.00455. PMID: 31354627; PMCID: PMC6639788.

15. Zhang CS#, Wang LX, Wang R, Liu Y, Song LM, Yuan JH, Wang B, Dong J*. The Correlation Between Circulating Ghrelin and Insulin Resistance in Obesity: A Meta-Analysis. Front Physiol. 2018 Sep 21;9:1308. doi: 10.3389/fphys.2018.01308. PMID: 30298019; PMCID: PMC6160589.

16. Fan XT#, Tian Z, Li SZ, Zhai T, Liu JL, Wang R, Zhang CS, Wang LX, Yuan JH, Zhou Y, Dong J*. Ghrelin Receptor Is Required for the Effect of Nesfatin-1 on Glucose Metabolism. Front Endocrinol (Lausanne). 2018 Oct 24;9:633. doi: 10.3389/fendo.2018.00633. PMID: 30405536; PMCID: PMC6207996.

四、 主持的科研项目

国家自然科学基金青年项目，8210033261，高压氧通过Nesfatin-1促进“中枢-脂肪”对话改善胰岛素抵抗的机制研究，2022/01–2024/12，24万元，在研，主持。

联系方式：青岛大学浩园医学综合楼C822室，yuanjunhua322@126.com