苗烁，女，病理生理学系，博士，硕士生导师。
2019年6月毕业于华中科技大学同济医学院，获医学博士学位。2019年7月进入青岛大学做博士后研究，合作导师王建勋教授。2021年入职青岛大学基础医学院病理生理学系。从事心血管疾病和肿瘤发生发展的分子机制研究。近年在Mol Cancer Ther，Mol Oncol，Cell Death Dis 等杂志发表SCI论文20余篇，主持国家自然科学青年基金、山东省博士后创新研究项目等课题。联系方式：shuomiaoshuomiao@163.com.
主要研究方向
1. 心肌损伤的分子机制与细胞死亡的调控机制
2. 血小板功能与疾病
主持科研项目
1. 国家自然科学基金青年基金
2. 山东省博士后创新研究项目
3. 青岛市博士后应用研究项目
代表性文章
1. Miao S, Zhang Q, Chang W, Wang J*. New Insights Into Platelet-enriched miRNAs: Production, Functions, Roles in Tumors, and Potential Targets for Tumor Diagnosis and Treatment. Mol Cancer Ther. 2021 Aug;20(8):1359-1366.
2. Shuo Miao, Meng Lu, Yue Liu , Dan Shu , Ying Zhu , Wei Song , Yuanyuan Ma, Rong Ma, Bixiang Zhang, Chao Fang, Zhang-Yin Ming*. Platelets are recruited to hepatocellular carcinoma tissues in a CX3CL1-CX3CR1 dependent manner and induce tumour cell apoptosis. Mol Oncol. 2020 Oct;14(10):2546-2559.
3. Shuo Miao, Dan Shu, Ying Zhu, Meng Lu, Qingsong Zhang, Youliang Pei, Ao-Di He, Rong Ma, Bixiang Zhang, Zhang-Yin Ming*. Cancer cell-derived immunoglobulin G activates platelets by binding to platelet FcγRIIa. Cell Death Dis. 2019 Feb; 10(2): 87.
4. Shuo Miao, Su-Mei Wang, Xue Cheng, Yao-Feng Li, Qing-Song Zhang, Gang Li, Song-Qing He, Xiao-Ping Chen, Ping Wu*. Erythropoietin promoted the proliferation of hepatocellular carcinoma through hypoxia induced translocation of its specific receptor. Cancer Cell Int. 2017; 17: 119.
5. Yang L, Miao S, Zhang J, Wang P, Liu G, Wang J*. The growing landscape of succinylation links metabolism and heart disease. Epigenomics. 2021 Feb;13(4):319-333.
6. Qingsong Zhang, Shuo Miao, Xihong Han, Chuanchang Li, Mengyang Zhang, Kai Cui, Tao Xiong, Zhong Chen, Chenghe Wang*, Hua Xu.MicroRNA-3619-5p suppresses bladder carcinoma progression by directly targeting β-catenin and CDK2 and activating p21.Cell Death Dis. 2018 Oct; 9(10): 960.
7. Zhang Q, Wang C, Miao S, Li C, Chen Z, Li F. Enhancing E-cadherin expression via promoter-targeted miR-373 suppresses bladder cancer cells growth and metastasis. Oncotarget. 2017 Sep 30;8(55):93969-93983.
8. Song W, Ma YY, Miao S, Yang RP, Zhu Y, Shu D, Lu M, Ma R, Ming ZY. Pharmacological actions of miltirone in the modulation of platelet function. Acta Pharmacol Sin. 2019 Feb;40(2):199-207.
