陈豪,青岛大学基础医学院人体显微结构学实验室,博士,高级实验师。
一、个人简介
陈豪,博士,高级实验师,主要从事组织胚胎学和炎症性角膜病研究。主持项目7项,其中省部级项目3项,包括山东省科学技术发展计划项目、山东省医药卫生科技发展计划项目和山东省重点研发计划项目子课题,自然资源部重点实验室项目2项,青岛市博士后资助项目和青岛大学医学院创新团队青年教师培育项目;同时,参与国家自然科学基金项目5项。发表研究论文36篇,其中SCI收录21篇,获授权国家发明专利4项。
二、主要研究方向
组织胚胎学,炎症性角膜病
三、代表性科研成果
(1)Chen Hao#,Hua Xiao-Min, Ze Bai-Chen, Wang Bin*, Wei Li*, The anti-inflammatory effects of asiatic acid in lipopolysaccharide-stimulated human corneal epithelial cells, International Journal of Ophthalmology, 2017, 10(2):179-185
(2)Chen Hao#, Zheng Zhou, Chen Peng, Wu Xiang Gen, Zhao Ge*, Inhibitory Effect of Extracellular Polysaccharide EPS-II from Pseudoalteromonas on Candida adhesion to Cornea in vitro,Biomedical and Environmental Sciences, 2012, 25(2):210-215
(3) Zhou Zheng, Hao Chen*, Huaiping Wang, Weiming Jiang, Qian Cao,Ning Du, Characterization of the complete mitochondrial genome of bull kelp,Nereocystis luetkeana. Mitochondrial DNA Part B,2019,4(1): 630-631
(4) Peng Chen#,Hao Chen#,Xiao-Jing Pan,Su-Zhen Tang,Yu-Jun Xia,Hui Zhang,Novel mutations in CRYBB1/CRYBB2 identified by targeted exome sequencing in Chinese families with congenital cataract, International Journal of Ophthalmology, 2018, 11(10):1577-1582.
(5) Chen Peng#, Chen Hao, Zang Xinjie, Chen Min, Jiang Haoran, Han Shasha, Wu Xianggen*, Expression of Efflux Transporters in Human Ocular Tissue, Drug Metabolism and Disposition,2013,41(11):1934-1948
(6) Zhao Ge#, Chen Hao, Song Zicheng,Yin Hongmei, Xu Yuanyuan, Chen Min*, Glial fibrillary acidic protein expression during HSV-1 infection in mouse cornea, Apmis,2014,122(2):128-135
(7) Wu Xianggen#*, Chen Hao, Jiang Haoran, Xu Yuanyuan, Liu Ting, Xu Lingjuan, Prophylactic Effect of Topical Fluoroquinolones in a Rabbit Model of Staphylococcus aureus Endophthalmitis, Journal of Ocular Pharmacology and Therapeutics,2012,28(2):186-193
(8) Sun SY#, Sun XY, Chen H, Zhao G, Etiological profiles and pathogen detection of infectious endophthalmitis, Zhonghua Yi Xue Za Zhi, 2012, 92(1):32-35
(9) Zhou Qingjun#, Chen Hao, Qu Mingli, Wang Qian, Yang Lingling, Xie Lixin*,Development of a novel ex vivo model of corneal fungal adherence,Graefes Archive for Clinical and Experimental Ophthalmology,2011,249(5):693-700
(10) Wu X-G#, Xin M, Chen H, Yang L-N, Jiang H-R, Novel mucoadhesive polysaccharide isolated from Bletilla striata improves the intraocular penetration and efficacy of levofloxacin in topical treatment of experimental bacterial keratitis (vol 62, pg 1152, 2010),Journal of Pharmacy and Pharmacology,2010,62(12):1813
(11) Wu Xiang-gen#*, Xin Meng, Chen Hao, Yang Li-na, Jiang Hao-ran, Novel mucoadhesive polysaccharide isolated fromBletilla striata improves the intraocular penetration and efficacy of levofloxacin in the topical treatment of experimental bacterial keratitis, Journal of Pharmacy and Pharmacology,2010,62(9):1152-1157
(12) Zhang Hongbo#, Chen Hao, Niu Jingyi, Wang Yiqiang, Xie Lixin*, Role of Adaptive Immunity in the Pathogenesis of Candida albicans Keratitis,Investigative Ophthalmology & Visual Science,2009,50(6):2653-2659
(13)陈豪,王斌,吴祥根,鲁晓晴,华晓敏,一种膦甲酸钠眼玻璃体腔内缓释药物,2017.08.16,中国, ZL201510245585.8
四、主持的科研项目
1.山东省重点研发专项子任务:共轭亚油酸异构体制备关键技术及其在脂质代谢紊乱医用食品中应用(2018YYSP024),2018/01-2020/12
2.青岛市博士后资助项目:积雪草酸调控人结肠细胞JAK2/STAT3信号通路的作用及机制研究,2019/01-2020/12
3.自然资源部重点实验室开放基金:南极冰藻光修复酶家族协同修复DNA紫外辐射损伤的分子作用机制研究(MBSMAT-2018-06),2018/01-2019/12
4.山东省医药卫生科技发展计划项目:病毒性角膜炎的LAMP法早期诊断及多糖对其防治研究(2014WS0441),2014/11-2016/12
5.山东省科技发展计划项目:海带微晶纤维素药用辅料的开发研究(2013YD21009),2013/01-2014/12
6.青岛大学医学院创新团队青年教师培育项目:南极适冷菌胞外多糖对真菌性角膜炎发病早期PI3K/AKT信号通路和相关炎症因子的影响研究(600201304),2013/01-2014/12
7.自然资源部重点实验室开放基金:南极嗜冷菌Marinomonas sp.NJ522超氧化物歧化酶基因的克隆与表达(MBSMAT-2012-08),2012/01-2013/12
五、科研奖励
无
六、主要荣誉称号
无
联系方式:E-mail:qddxchenhao@qdu.edu.cn