董静

作者: 时间:2019-04-26 点击数:

董静,博士,教授,博士生导师,青岛大学生理学教研室教师。山东医科大学学士、比利时自由大学硕士、比利时鲁汶大学和青岛大学联合培养博士。

主要从事与糖尿病、肥胖、代谢紊乱相关的研究,探讨与摄食相关的脑肠肽参与中枢摄食及外周脂肪代谢的机制和信号通路。承担本科生《生理学》《医学伦理学》、硕士研究生《高级生理学》、博士研究生《高级生理学》的教学工作。参与《生理科学进展》、《人体生理学》的编著工作。指导本科生获得第五届全国大学生基础医学创新论坛暨实验设计大赛二等奖,连续多年被评为“学生最喜爱的老师”。近年来主持国家自然科学基金项目两项、山东省自然科学基金一项、青岛市自然基金重点项目一项。近五年在国际专业学术期刊发表研究论文十余篇。

科研项目

1.Nesfatin-1通过脑桥外侧臂旁核(LPBN)参与1型糖尿病小鼠低血糖危象的调节及其机制的研究(31872791),国家自然科学基金,2019.01-2022.12,60万元,董静,刘均利,陈曦,袁骏华,张彩顺,王瑞,王柳欣,宋莉敏,刘媛

2.中枢nesfatin-1对2型糖尿病小鼠脂肪代谢调节机制及相关中枢环路的研究(31371168),国家自然科学基金,2014.01-2017.12,77万元,董静,刘均利,蒋正尧,仲伟珍,夏蕴秋,张迪,李青

近五年发表文章:

1、Xu HC, Pang YC, Chen JW, Cao JY, Sheng Z, Yuan JH, Wang R, Zhang CS, Wang LX, Dong J. Systematic review and meta-analysis of the change in ghrelin levels after Roux-en-Y gastric bypass. Obesity Surgery. 2019 Jan 25

2、Rui Wang†, Junhua Yuan†, Caishun Zhang, Liuxin Wang, Yuan Liu, Limin Song, Weizhen Zhong, Xi Chen* and Jing Dong*. Neuropeptide Y-Positive Neurons in the Dorsomedial Hypothalamus Are Involved in the Anorexic Effect of Angptl8. Frontiers in Molecular Neuroscience. 2018 December 18.

3、RUI WANG*, LIUXIN WANG*, CAISHUN ZHANG, YAN ZHANG, YUAN LIU, LIMIN SONG, RUIXIA MA and JING DONG. L‑carnitine ameliorates peripheral neuropathy in diabetic mice with a corresponding increase in insulin‑like growth factor‑1 level. Molcular Medicine Report. 2018 October 22.

4、Xin-Tong Fan†, Zhao Tian†, Shi-Zhen Li†, Ting Zhai†, Jun-Li Liu, Rui Wang, Cai-Shun Zhang, Liu-Xin Wang, Jun-Hua Yuan, Yu Zhou and Jing Dong*. Ghrelin Receptor Is Required for the Effect of Nesfatin-1 on Glucose Metabolism. Frontiers in Endocrinology. 2018 October 24.

5、Cai-Shun Zhang†, Liu-Xin Wang†, Rui Wang, Yuan Liu, Li-Min Song, Jun-Hua Yuan, Bin Wang* and Jing Dong*. The Correlation Between Circulating Ghrelin and Insulin Resistance in Obesity: A Meta-Analysis. Frontiers in physiology. 2018 September 21.

6、Jun-hua Yuan#, Xi Chen#, Jing Dong*, Di Zhang, Kun Song, Yue Zhang, Guang-bo Wu, Xi-hao Hu, Zhang-yao Jiang and Peng Chen. Nesfatin-1 in the Lateral Parabrachial Nucleus Inhibits Food Intake, Modulates Excitability of Glucosensing Neurons, and Enhances UCP1 Expression in Brown Adipose Tissue. Frontiers in Physiology, 2017, 8.

7、Ting Zhai, Shi-Zhen Li, Xin-Tong Fan, Zhao Tian, Xiao-Qing Lu, Jing Dong*. Circulating Nesfatin-1 Levels and Type 2 Diabetes: A Systematic Review and Meta-Analysis. Journal of Diabetes Research, 2017, 2017(10): 1-8.

8、Wang YY#, Zhang D#, Jiang ZY, Lu XQ, Zheng X, Yu YJ, Wang YG*, Dong J*. Positive association between betatrophin and diabetic retinopathy risk in type 2 diabetes patients. Horm Metab Res. 2016 Feb 10.

9、Chen X#*, Jiang ZY, Dong J. Nesfatin-1acts on the dopaminergic reward pathway to inhibit food intake. 7th International Congress on Stress Response in Biology and Medicine, 2015.9.15-19.

10、Yu YJ, Yuan JH, Han W, Ma HY, Song K, Wang J, Wang L, Zhang Y, Chen X, Jiang ZY, Dong J*. Betatrophin attenuates acute hyperglycemia and lower the mortality in streptozotocin-induced type 1diabetic neonatal rats. 7th International Congress on Stress Response in Biology and Medicine, 2015.9.15-1

11、Dong J#, Guan HZ#, Jiang ZY*, Chen X*. Nesfatin-1 influences the excitability of glucosensing neurons in the dorsal vagal complex and inhibits food intake. PLoS One. 2014, 9(6):e98967.

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