主 要 学 术 成 果:
科研项目:
1、HCMV感染通过EGFR介导的MAPK-ATF5通路影响脑胶质瘤干细胞增殖及分化的机制/国家自然科学基金
2、海藻纤维在制备新型医用止血敷料中的研发/山东省科技厅项目
3、动物源病原体的发现及其对人类致病性研究/国家自然科学基金
著作教材:
1、病原生物学与免疫学/人民卫生出版社 主编
期刊论文:
1、DNA methylation level of promoter region of activating transcription factor 5 in glioma/Journal of Zhejiang University-SCIENCE B /16(9)
2、Role of Treg Cells and TGF-β1 in Patients with Systemic Lupus Erythematosus: A Possible Relation with Lupus Nephritis/Immunol Invest. 2012;41(1):15-27
3、Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis. Rheumatol Int,2012,32,949-958
4、Papillary tumor of the pineal region: A case report and review of the literature/EXPERIMENTAL AND THERAPEUTIC MEDICINE/10
5、Sero-epidemiological survey of human cytomegalovirus-infected children in Weifang (Eastern China) between 2009 and 2012.Virol [J]. 2013,10(1):42.
6、Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes. NeuroReport. 2013, 24(10):526-35
7、Interference with ATF5 Function Enhances the Sensitivity of Human Pancreatic Cancer Cells to Paclitaxel-induced Apoptosis. Anticancer Res. 2012 Oct;32(10):4385-94
8、ATF5 Is Overexpressed in Epithelial Ovarian Carcinomas and Interference With Its Function Increases Apoptosis Through the Downregulation of Bcl-2 in SKOV-3 Cells/Int J Gynecol Pathol.2012;31(6):532-7
9、HCMV Induces Dysregulation of Glutamate Uptake and Transporter Expression in Human Fetal Astrocytes. Neurochem Res, 2014. 39(12): 2407-18
10、Upregulation of Toll like receptor 2 expression in colorectal cancer infected by human cytomegalovirus/ONCOLOGY LETTERS/9: 365-370, 2015
获奖情况:
1、HCMV感染致病机制及相关的婴儿肝炎综合征/山东省科技进步奖
2、Th17/Treg免疫偏移在狼疮性肾炎发病中的免疫机制作用/青岛市科技进步二等奖
3、HCMV感染致病机制及相关的婴儿肝炎综合征/青岛市科学技术奖
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