谭晓华，病理学系，博士，副教授，硕士生导师

一、 个人简介

吉林大学白求恩医学部病理学与病理生理学系博士，美国密歇根大学病理学系访问学者。承担《病理学》《人体显微结构学实验》及《Pathology》等课程的教学。主持国家自然科学基金青年项目，山东省自然科学基金面上项目等多项科研项目。在Nephrol Dial Transplant, J CELL MOL MED, Front Cell Dev Biol等杂志发表多篇研究论文。

二、 主要研究方向

急性肾损伤及肾间质纤维化发生发展过程中的分子调控机制及治疗方法

三、代表性科研成果

(1) Xiaohua Tan^{# *}, Qianyu Tao, Guixiu Li, Lijun Xiang, Xiaomeng Zheng, Tianzhen Zhang, Cuijiao Wu, Dequan Li^*. Fibroblast growth factor 2 attenuates renal ischemia-reperfusion injury via inhibition of endoplasmic reticulum stress. Front Cell Dev Biol. 2020 Mar 24;8:147.

(2) Xiaohua Tan^#, Lixia Yu, Ruo Yang, Qianyu Tao, Lijun Xiang, Jian Xiao^*, Jin-San Zhang^*. Fibroblast growth factor 10 attenuates renal damage by regulating ER stress after ischemia-reperfusion injury. Front. Pharmacol. 2020 Feb 7;11:39.

(3) Yaolin Song^#, Qianyu Tao, Lixia Yu, Ling Li, Tingting Bai, Xiaoxiao Song, Haiqi Hu, Yulin Li^*, Xiaohua Tan^*. Activation of autophagy contributes to the renoprotective effect of postconditioning on acute kidney injury and renal fibrosis，Biochem Biophys Res Commun. 2018, Oct 12;504(4):641-646.

(4) Xiao-hua Tan^#, Xiao-meng Zheng^#, Li-xia Yu, Jian He, Hong-mei Zhu, Xiu-ping Ge, Fa-Qing Ye, Saverio Bellusci, Jian Xiao, Xiao-kun Li^*, Jin-san Zhang^*, Fibroblast growth factor 2 protects against renal ischaemia/reperfusion injury by attenuating mitochondrial damage and proinflammatory signaling. J CELL MOL MED,2017, 21(11): 2909-2925.

(5) Shuxian Zhang^#, Xiaohua Tan^#, Yan Chen, Xiuying Zhang*, Post-conditioning protects renal fibrosis by attenuating oxidative stress induced mitochondrial injury. Nephrol Dial Transplant, 2017, 32(10): 1628-1636.

(6) Xiaohua Tan^#, Ruili Yin^#, Yan Chen, Dan Gao, Xiuying Zhang^*. Postconditioning attenuates renal ischemia-reperfusion injury by mobilization of stem cells. J Nephrol, 2015, 28(3): 289-98.

(7) Xiaohua Tan^#, Lei Zhang^#, Yunpeng Jiang, Yujia Yang, Wenqi Zhang, Yulin Li^*, Xiuying Zhang^*, Postconditioning ameliorates mitochondrial DNA damage and deletion after renal ischemic injury, Nephrol Dial Transplant, 2013, 28(11): 2754-65.

四、主持的科研项目

1. 山东省自然科学基金面上项目，ZR2020MH077，FGF10/FGFR2b 信号通路对急性肾损伤后间质纤维化的保护作用和机制研究，2021.01-2023.12，10万元，在研，主持

2. 国家自然科学基金青年项目，81500519，FGF7通过动员内源性干细胞促进肾脏损伤修复的机制，2016/01-2018/12，18万元，结题，主持

联系方式：E-mail: xiaohuatan@foxmail.com